PUBLICATIONS
[33] S. Dasaro, A. Singh, P. Vlachos, K. Ristroph. “Mechanistic insights into how mixing factors govern polyelectrolyte-surfactant complexation in RNA lipid nanoparticle formulation.” Journal of Colloid and Interface Science (2024) DOI: 10.1016/j.jcis.2024.08.150.
[32] K. Ristroph. “Drugs need to be formulated with scale-up in mind.” Journal of Controlled Release (2024) DOI: 10.1016/j.jconrel.2024.07.016.
[31] M. Baghbanbashi, H. Shiran, A. Kakkar, G. Pazuki, K. Ristroph. “Recent Advances in Drug Delivery Applications of Aqueous Two-Phase Systems.” PNAS Nexus (2024) DOI: 10.1093/pnasnexus/pgae255.
[30] G. Lowry, J. P. Giraldo, N. Steinmetz, A. Avellan, G. Demirer, K. Ristroph, G. Wang, C. Hendren, C. Alabi, A. Caparco, W. da Silva, I. González-Gamboa, K. Grieger, S. Jeon, M. Khodakovskaya, H. Kohay, V. Kumar, R. Muthuramalingam, H. Poffenbarger, S. Santra, R. Tilton, J. White. “Opportunities and Challenges to Realizing Nano-enabled Precision Delivery in Plants.” Nature Nanotechnology (2024). DOI: 10.1038/s41565-024-01667-5
[29] K. Yamada, K. Ristroph, Y. Kaneko, H. Lu, R. Prud’homme, H. Sato, S. Onoue. "Pharmacokinetic control of orally dosed cyclosporine A with mucosal drug delivery system." Biopharmaceutics and Drug Disposition (2024) DOI: 10.1002/bdd.2388
[28] L. S. B. L. Oliveira and K. Ristroph. "Critical Review: Uptake and Translocation of Organic Nanodelivery Vehicles in Plants." Environmental Science and Technology (2024) DOI: 10.1021/acs.est.3c09757
[27] K. Ristroph, Y. Zhang, V. Nava, J. Wielinski, H. Kohay, A. Kiss, J. Thieme, and G. Lowry “Flash NanoPrecipitation as an Agrochemical Nanocarrier Formulation Platform: Phloem Uptake and Translocation after Foliar Administration.” ACS Agricultural Science and Technology (2023) DOI: 10.1021/acsagscitech.3c00204
[26] S. Jeon, Y. Zhang, C. Castillo, V. Nava, K. Ristroph, B. Therrien, L. Meza, G. Lowry, J. P. Giraldo. “Targeted Delivery of Sucrose-Coated Nanocarriers with Chemical Cargoes to the Plant Vasculature Enhances Long-Distance Translocation.” Small (2023) DOI: 10.1002/smll.202304588
[25] N. Caggiano, S. Nayagam, L. Wang, B. Wilson, P. Lewis, S. Jahangir, R. D. Priestley, R. K. Prud’homme, and K. Ristroph. “Sequential Flash NanoPrecipitation for the scalable formulation of stable core-shell nanoparticles with core loadings up to 90%.” International Journal of Pharmaceutics (2023) DOI: 10.1016/j.ijpharm.2023.122985
[24] M. Armstrong, L. Wang, K. Ristroph, C. Tian, J. Yang, L. Ma, S. Panmai, D. Zhang, K. Nagapudi, and R. K. Prud’homme. "Formulation and Scale-up of Fast-Dissolving Lumefantrine Nanoparticles for Oral Malaria Therapy." J. Pharmaceutical Sciences (2023) DOI: 10.1016/j.xphs.2023.04.003
[23] Y. Zhang, L. Fu, M. R. Martinez, H. Sun, V. Nava, J. Yan, K. Ristroph, S. E. Averick, B. Marelli, J. P. Giraldo, K. Matyjaszewski, R. D. Tilton, and G. V. Lowry. "Temperature-Responsive Bottlebrush Polymers Deliver a Stress-Regulating Agent In Vivo for Prolonged Plant Heat Stress Mitigation." ACS Sust. Chem. Eng. (2023) DOI:
[22] K. Ristroph, S. McManus, G. Shetye, S. Cho, D. Lee, Z. Szekely, P. Sinko, S. Franzblau, R. K. Prud'homme. “Targeted antitubercular peptide nanocarriers prepared by Flash NanoPrecipitation with hydrophobic ion pairing.” Advanced Materials Technologies (2022) DOI: 10.1002/admt.202101748
[21] N. Khan, M. Salim, S. Binte, A. Bakar, K. Ristroph, R. K. Prud'homme, A. Hawley, B. J. Boyd, A. J. Clulow. “Small-volume in vitro lipid digestion measurements for assessing drug dissolution in lipid-based formulations using SAXS.” International Journal of Pharmaceutics: X (2022) DOI: 10.1016/j.ijpx.2022.100113
[20] K. Yamada, K. Ristroph, Y. Kaneko, H. Lu, Y. Seto, H. Sato, R. K. Prud’homme, S. Onoue. “Clofazimine-loaded Mucoadhesive Nanoparticles Prepared by Flash NanoPrecipitation for Strategic Intestinal Delivery.” Pharmaceutical Research (2021) DOI: 10.1007/s11095-021-03144-3
[19] K. Ristroph, J. Ott, L. Issah, B. Wilson, A. Kujović, S. Datta, R. K. Prud’homme. “Reversible pH-driven flocculation of amphiphilic polyelectrolyte-coated nanoparticles for rapid filtration and concentration.” ACS Applied Nano Materials (2021) DOI: 10.1021/acsanm.1c00707
[18] C. Markwalter, R. Pagels, A. Hejazi, K. Ristroph, J. Wang, K. Chen, J. Li, R. K. Prud’homme. “Sustained release of peptides and proteins from polymeric nanocarriers produced by inverse Flash NanoPrecipitation.” Journal of Controlled Release (2021) DOI: 10.1016/j.jconrel.2021.04.002
[17] K. Ristroph, M. Salim, A. Clulow, B. Boyd, R. K. Prud’homme. “Chemistry and geometry of counterions used in hydrophobic ion pairing control internal liquid crystal phase behavior and thereby drug release.” Molecular Pharmaceutics (2021) DOI: 10.1021/acs.molpharmaceut.0c01132
[16] K. Ristroph, P. Rummaneethorn, B. Johnson-Weaver, H. Staats, and R. K. Prud’homme. “Highly-loaded protein nanocarriers prepared by Flash NanoPrecipitation with hydrophobic ion pairing.” International Journal of Pharmaceutics (2021) DOI: 10.1016/j.ijpharm.2021.120397
[15] K. Ristroph, M. Salim, B. Wilson, A. Clulow, B. Boyd, R. K. Prud’homme. “Internal liquid crystal structures in nanocarriers containing drug hydrophobic ion pairs dictate drug release.” Journal of Colloid and Interface Science (2020) DOI: 10.1016/j.jcis.2020.08.045
[14] M. McPhillie, Y. Zhou, M. Hickman, J. Gordon, C. Weber, Q. Li, P. Lee, K. Amporndanai, R. Johnson, H. Darby, S. Woods, Z. Li, R. Priestley, K. Ristroph, et al. “Potent tetrahydroquinolone eliminates apicomplexan parasites.” Frontiers in Cellular and Infection Microbiology (2020) DOI: 10.3389/fcimb.2020.00203
[13] D. Kozuch*, K. Ristroph*, R. Prud’homme, P. Debenedetti. “Insights into hydrophobic ion pairing from molecular simulation and experiment.” ACS Nano (2020) DOI: 10.1021/acsnano.0c01835
[12] K. Ristroph and R. K. Prud’homme. “Hydrophobic ion pairing: encapsulating small molecules, peptides, and proteins into nanocarriers.” Nanoscale Advances (2019) DOI: 10.1039/c9na00308h
[11] K. Ristroph, J. Feng, S. McManus, Y. Zhang, K. Gong, H. Ramachandruni, C. White, R. K. Prud’homme. “Spray drying OZ439 nanoparticles to form stable, water-dispersible powders for oral malaria therapy.” Journal of Translational Medicine (2019) DOI: 10.1186/s12967-019-1849-8
[10] H. Sato, Y. Kaneko, K. Yamada, K. Ristroph, H. Lu, Y. Seto, H.-K. Chan, R. Prud’homme, S. Onoue. “Polymeric NCs with mucus-diffusive and mucus-adhesive properties to control pharmacokinetic behavior of orally-dosed cyclosporine A.” Journal of Pharmaceutical Science (2019) DOI: 10.1016/j.xphs.2019.10.043
[9] M. Salim, G. Ramirez, A. Clulow, Y. Zhang, K. Ristroph, J. Feng, S. McManus, A. Hawley, R. Prud’homme, B. Boyd. “Solid state behaviour and solubilisation of Flash NanoPrecipitated clofazimine particles during the dispersion and digestion of milk-based formulations.” Mol. Pharm. (2019) DOI: 10.1021/acs.molpharmaceut.9b00276
[8] J. Feng, Y. Zhang, S. McManus, R. Qian, K. Ristroph, H. Ramachandruni, K. Gong, C. White, A. Rawal, R. K. Prud’homme. “Amorphous nanoparticles by self-assembly: processing for controlled release of hydrophobic molecules.” Soft Matter (2019) DOI: 10.1039/c8sm02418a
[7] C. Markwalter, R. Pagels, B. Wilson, K. Ristroph, R. K. Prud'homme. “Flash NanoPrecipitation for the encapsulation of hydrophobic & hydrophilic compounds in polymeric nanoparticles.” Journal of Visualized Experiments (2019) DOI: 10.3791/58757
[6] H. Lu*, K. Ristroph*, E. Dobrijevic*, J. Feng, S. McManus, Y. Zhang, W. Mulhearn, H. Ramachandruni, R. K. Prud’homme. “Encapsulation of OZ439 into nanoparticles for supersaturated drug release in oral malaria therapy.” ACS Infectious Diseases (2018) DOI: 10.1021/acsinfecdis.7b00278
[5] H. Lu, P. Rummaneethorn, K. Ristroph, R. Prud’homme, “Hydrophobic ion pairing of peptide antibiotics for processing into controlled release nanocarrier formulations.” Molecular Pharmaceutics (2018) DOI: 10.1021/acs.molpharmaceut.7b00824
[4] H. Lu, E. Pearson, K. Ristroph, G. Duncan, L. Ensign, J. Suk, J. Hanes, R. K. Prud’homme. “Pseudomonas aeruginosa pyocyanin production reduced by quorum-sensing inhibiting nanocarriers.” International Journal of Pharmaceutics (2018) DOI: 10.1016/j.ijpharm.2018.03.058
[3] J. Feng, Y. Zhang, S. McManus, K. Ristroph, H. Lu, K. Gong, C. White, R. K. Prud’homme. “Rapid recovery of clofazimine-loaded nanoparticles with long-term storage stability as anti-cryptosporidium therapy.” ACS Applied Nano Materials (2018) DOI: 10.1021/acsanm.8b00234
[2] Y. Zhang, J. Feng, S. McManus, H. Lu, K. Ristroph, E. Cho, E. Dobrijevic, H.-K. Chan, R. K. Prud’homme. “Design and solidification of fast-releasing clofazimine nanoparticles for treatment of cryptosporidiosis.” Molecular Pharmaceutics (2017) DOI: 10.1021/acs.molpharmaceut.7b00521
[1] K. Ristroph, C. Astete, E. Bodoki, C. Sabliov. “Zein nanoparticle uptake by hydroponically grown soybean plants.” Environmental Science & Technology (2017) DOI: 10.1021/acs.est.7b03923